By Eamon Shamil, Praful Ravi, Ashish Chandra
A 27-year-old Ghanaian lady offers within the emergency division with a three-day background of headache, nausea, and obscure reduce stomach discomfort. She has no major prior clinical background, yet is eight-weeks pregnant together with her first baby. She lives in London and lower back from a visit to Ghana two weeks in the past. you've been assigned her preliminary assessment...
100 instances in medical Pathology offers a hundred scientific situations usually obvious via clinical scholars and junior medical professionals within the emergency division, outpatient hospital, or regularly perform within which an knowing of the underlying medical pathology is crucial to arriving on the right analysis. A succinct precis of the patient's heritage, exam, and preliminary investigations—histopathology, chemical pathology, haematology, microbiology, and scientific immunology as appropriate—is by means of questions about every one case, with specific emphasis at the interpretation of the consequences and the arriving at a clinicopathologic analysis. the reply contains a precise dialogue on each one subject, delivering an important revision reduction in addition to a realistic advisor for college kids and junior medical professionals.
Making fast and acceptable scientific judgements, and selecting the simplest plan of action to take for that reason, is among the most vital and demanding elements of teaching to develop into a physician. those true-to-life circumstances will educate scholars and junior medical professionals to acknowledge very important medical stipulations, to request the suitable pathological research and properly interpret these effects, and, consequently, to increase their diagnostic and administration skills.
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Additional resources for 100 Cases in Clinical Pathology
INVESTIGATIONS The patient’s most recent full blood count and renal function are within normal limits. Questions 1. Describe the principles of screening and what criteria are used to determine the quality of a screening test. 2. What is the PSA screening test, and what are the ways in which it may be used in a more accurate fashion? 3. What is the current evidence on PSA screening for prostate cancer? Would you recommend it in this case? 19 100 Cases in Clinical Pathology ANSWER 7 Screening is a public health service where members of the whole population are offered a test that helps identify those at higher risk of the disease so that they may undergo further testing.
35 Case 12: Excessive hair growth and infertility CASE 12: EXCESSIVE HAIR GROWTH AND INFERTILITY History A 22-year-old woman presents to her GP because she is embarrassed by ‘excessive hair growth’ on her upper lip, lower abdomen and thighs. She has waxed her legs and body and shaved her upper lips weekly throughout her teenage years. On direct questioning, she confesses to her periods being irregular since menarche and that she is having difficulty conceiving despite regular unprotected sexual intercourse with her partner for the past year.
Despite these modifications, PSA screening for prostate cancer is not currently recommended by the National Institute for Health and Clinical Excellence (NICE) in the UK. The current evidence on PSA screening is very controversial. A large European r andomized study found that although PSA screening did significantly reduce mortality from prostate cancer, more than 1000 men would have to be screened and 37 cancers would need to be detected in order to prevent one death from prostate cancer over 11 years of followup.
100 Cases in Clinical Pathology by Eamon Shamil, Praful Ravi, Ashish Chandra