Download e-book for iPad: Anaerobiosis and stemness : an evolutionary paradigm for by Zoran Ivanovic, Marija Vlaski-Lafarge

By Zoran Ivanovic, Marija Vlaski-Lafarge

ISBN-10: 0128005408

ISBN-13: 9780128005408

ISBN-10: 0128006110

ISBN-13: 9780128006115

Anaerobiosis and Stemness: An evolutionary paradigm presents a context for knowing the various complexities and evolutionary gains of stem cells and the medical implications of anaerobiosis stem cells. Combining theoretical and experimental wisdom, the authors offer a wide figuring out of ways the absence or low focus of oxygen can play an influential function within the upkeep and self-renewal of stem cells and stem phone differentiation. This knowing has medical implications for the fields of regenerative drugs, melanoma biology and transplantation, in addition to cellphone engineering and cellphone treatment. Anaerobiosis and Stemness is a crucial source for stem mobilephone and developmental biologists alike, in addition to oncologists, melanoma biologists, and researchers utilizing stem cells for regeneration.

  • Highlights the molecular and evolutionary good points of stem cells which cause them to so very important to all organic research
  • Explores equipment of isolation, characterization, activation, and upkeep of stem cells
  • Includes versions for medical program in regenerative drugs, melanoma treatment, and transplantation

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Blood 2010;116:375–85. [53] Takubo K, Goda N, Yamada W, Iriuchishima H, Ikeda E, Kubota Y, et al. Regulation of the HIF-1alpha level is essential for hematopoietic stem cells. Cell Stem Cell 2010;7:391–402. [54] Jang YY, Sharkis SJ. A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche. Blood 2007;110:3056–63. [55] Forristal CE, Nowlan B, Jacobsen RN, Barbier V, Walkinshaw G, Walkley CR, et al. HIF-1α is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1α.

Spatial localization of transplanted hemopoietic stem cells: inferences for the localization of stem cell niches. Blood 2001;97:2293–9. [34] Askenasy N, Farkas DL. Optical imaging of PKH-labeled hematopoietic cells in recipient bone marrow in vivo. Stem Cells 2002;20:501–13. [35] Nilsson SK, Dooner MS, Tiarks CY, Weier HU, Quesenberry PJ. Potential and distribution of transplanted hematopoietic stem cells in a nonablated mouse model. Blood 1997;89:4013–20. [36] Arai F, Hirao A, Ohmura M, Sato H, Matsuoka S, Takubo K, et al.

86] Yamaleyeva LM, Guimaraes-Souza NK, Krane LS, Agcaoili S, Gyabaah K, Atala A, et al. Cell therapy with human renal cell cultures containing erythropoietin-positive cells improves chronic kidney injury. Stem Cells Transl Med 2012;1:373–83. [87] Evans SM, Schrlau AE, Chalian AA, Zhang P, Koch CJ. Oxygen levels in normal and previously irradiated human skin as assessed by EF5 binding. J Invest Dermatol 2006;126:2596–606. [88] Dayan F, Roux D, Brahimi-Horn MC, Pouyssegur J, Mazure NM. The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha.

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Anaerobiosis and stemness : an evolutionary paradigm for therapeutic applications by Zoran Ivanovic, Marija Vlaski-Lafarge


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